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Ld-type tumors and 15 BRAF-mutant tumors from the TUH and NCCH cohort) and a validation set (30 KRAS/BRAF-wild type tumors and four BRAF-mutant tumors from the TUH cohort) (Table 1). Using the screening set, we found nine up-regulated miRNAs (median, > 1.5-fold) and 13 down-regulated miRNAs (median,
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Ecent studies using phosphomimetic mutants of CNKSR1 have identified phosphorylation sites in the scaffold critical for nuclear translocation and activation of MAPK pathway genes [21]. However, to date all CNKSR1 analysis in the context of pancreatic cancer has been performed at a molecular level with no translational or clinically oriented application. Using pancreatic tumor tissues from three i
Shown in Table 1. The atomic coordinates have been deposited in the RCSB Protein Data Bank under accession numbers 4NXD, 4H10, 4NWG, 4GWF, 4NWF, and 4H34. All figures were produced using PyMOL (http://www.pymol.org).Table 1 Summary of crystallographic data and refinement statisticsParameters Data collection: Resolution, (? Outermost resolution shell, (? Space group Unit cell parameters a, (? b, (
Me over time Baseline Plaque volume (cm3) ?R Plaque volume (cm3) ?Z TVV (cm3) ?R TVV (cm3) ?Z *p
Ucted. Outcomes: In total 1117 students of 13 experimental schools and 758 students of 11 manage schools participated within the study. Short- and longer-term favourable intervention effects had been identified on fruit consumption (mean distinction in between experimental and handle group 0.15 servings at each posttests). Relating to fruit juice consumption, only short-term favourable effects ha

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