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No association was found between unnormalized parent drug clearance values and the body surface areas. In all but one patient, the peak CA4P concentration was reached within 3?min after the end of infusion (i.e. tmax�� 3?min). The CA4P AUC(0,t) (in most subjects, t was 4?h) and Cmax values (0.25??m?h and 0.18??m, respectively) at 10?mg?m?2 increased linearly to 3.16??m?h and 1.58??m, respectively,

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