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Search results for cpi-613

Sured with VesselMass software. Changes in all parameters between groups from baseline to year one were compared by unpaired t-test. Changes in LDL were compared with changes in plaque parameters by linear regression. Results: LDL at baseline was higher in the R group (120 ?37) than the Z group (100 ?27) mg/dl, p = 0.02. The decrease in LDL at one year was significantly greater in R (-41 ?37) tha
Osclerotic plaque volume in the superficial femoral artery when compared to those already treated with statin given ezetimibe. Reverse vessel wall remodeling was noted among PAD patients newly treated with statins compared to those with ezetimibe added to preexisting statin therapy. Thus the degree and/or mechanism of LDL lowering rather than the final LDL achieved may be important in halting ath
IniumDTPA). LGE was determined by a blinded, independent reader using grayscale thresholds of both 4 and 6 standard deviations (SD) above the mean of normal, remote myocardium. BZ was determined as the difference between the 4 SD and 6 SD thresholds. All subjects underwent 24-h ambulatory Holter electrocardiogram (ECG) within 7.8 ?8.3 weeks of the CMR Results: The amount of myocardial scarring (6
IniumDTPA). LGE was determined by a blinded, independent reader using grayscale thresholds of both 4 and 6 standard deviations (SD) above the mean of normal, remote myocardium. BZ was determined as the difference between the 4 SD and 6 SD thresholds. All subjects underwent 24-h ambulatory Holter electrocardiogram (ECG) within 7.8 ?8.3 weeks of the CMR Results: The amount of myocardial scarring (6
Exercise performance in patients with peripheral arterial disease (PAD); however, the mechanism of action is unclear. Purpose: We sought to use CMR to study the relationship between LDL reduction and superficial femoral artery (SFA) plaque burden in patients with PAD treated with lipid lowering therapy over the course of 1 year. Methods: 63 patients with mild-to-moderate symptomatic PAD (mean age
Sured with VesselMass software. Changes in all parameters between groups from baseline to year one were compared by unpaired t-test. Changes in LDL were compared with changes in plaque parameters by linear regression. Results: LDL at baseline was higher in the R group (120 ?37) than the Z group (100 ?27) mg/dl, p = 0.02. The decrease in LDL at one year was significantly greater in R (-41 ?37) tha
Ent in 119 patients (82 ). There was no significant association with the extent of myocardial scarring and the occurrence of NSVTs, couplets, and PVCs (overall p = 0.05). However the extent of BZ was significantly associated with the occurrence of NSVTs, couplets and PVCs (overall p
As the search model. The wild type SHP2 and D61G, E139D, Y279C and Q506P mutant structures were determined by molecular replacement, using the structure of the N308D SHP2 mutant as a search model. Following the initial rigid body refinement, interactive cycles of model building and refinement were performed by using COOT [40] and Buster-TNT [41] software. Special attention was paid to the mutatio


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